But
at Hopkins a new MRI-a compact, operating-room version of the imaging device-is
shifting craniopharyngioma outcomes, and that of other tumors such as low-grade
gliomas, to patients' favor. The device essentially delineates what needs
removing. "Our intraoperative MRI's been in use less than half a year,"
says neurosurgeon Alessandro Olivi, M.D., "but we already see tumor removal
is far more thorough."
Take the story of Steve Brooks, 42, a recent patient of Olivi's. Three years
ago, the husband and father had become leaden with fatigue. Endocrinologists
at his local medical center said he had low thyroid hormone. "I did," Brooks
says, "but nothing seemed to correct it."
Scans at a nearby hospital suggested a pituitary tumor, and Brooks underwent
surgery via the transsphenoidal approach: through the nose, sinus roof and
floor of the skull to the sella. The fact that the tumor turned out to be
a craniopharyngioma wasn't troubling. He still felt fine afterward.
But within months, Brooks had problems driving. "I'd head down the road
and the painted lines would cross." Also, his peripheral vision was suspect.
It was clear that the regrowing tumor threatened his sight. When Brooks
came to Hopkins, Olivi scheduled immediate surgery-a right fronto-temporal
craniotomy-to save the man's vision. A second transsphenoidal surgery would've
provided total access, Olivi explains, but was risky so soon after Brooks'
earlier operation. "My goal was to relieve the pressure on the optic nerves,"
says Olivi, though he knew some tumor would remain out of reach.
This April, with Brooks'
vision fine and his previous surgeries healed, Olivi went back for the rest.
But this time he had the intra-op MRI at hand. In a newly refitted and shielded
OR, the machine's magnet snapped into place hydraulically from beneath the
operating table, cradling Brooks' head for a pre-op scan.
"Seeing what the MRI enhanced let me evaluate the margins of the tumor and
possible residual tissue," says Olivi. "Before closing, we again raised
the magnet and scanned the surgical site. It was clean. And follow-up MRI
with the higher-resolution hospital scanner the next day confirmed it."
As for Brooks, who's back at work, the photo above says it all.
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