GABAPENTIN
(Neurontin)
Indication:
Gabapentin has been found to be effective for complex
partial seizures and complex partial seizures that secondarily generalize.
Possible side effects: Side effects that have been most frequently
reported with gabapentin have been lethargy, fatigue, dizziness, imbalance, tremor,
nausea and/or vomiting. There does not seem to be any significant interaction
with other commonly used anticonvulsants.
You need to be aware that with any changes in your anticonvulsant therapy, there
may be an increase in seizure frequency. Keep in mind that side effects vary with
individuals. If you have any problem with medication, you should let your doctor
know, whether or not it is a problem listed above.
Dosage: Neurontin is supplied in 100mg white capsules, 300mg
yellow capsules, and 400mg orange capsules. The recommended dose is between 900mg
and 1800mg per day in three divided doses. Doses of up to 3600mg per day have
been well tolerated in some patients. If you are not having side effects and still
are having seizures, your doctor may consider using doses of 3600mg or higher.
Drug Interactions: Antacids decrease the absorption of gabapentin.
Separate administration time by 2 hours. Other drugs may affect or be affected
by gabapentin.
Blood levels: The expected ranges for gabapentin tend to be in
the 3-20 mcg/ml range.