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Some of the Major Research Accomplishments
of the Department of Neurology
Mechanisms of
acetylcholine transmission and myasthenia gravis.
(Daniel Drachman).
Establishment
of Neurological Intensive Care Unit. (Daniel
Hanley, Cecil Borel)
Development of
ketogenic diet for intractable epilepsy.
(John Freeman, Patty Vining)
Biochemical and
genetic basis of adrenoleukodystrophy.
(Hugo and Ann Moser)
Treatment and
biological basis of Tourette's syndrome.
(Harvey Singer)
Epidemiology and
pathophysiological mechanisms of HIV-associated dementia.
(Richard Johnson, Justin McArthur et al)
Mechanisms of
neuronal damage in ALS. (Jeffrey
Rothstein)
Elucidation of
immunopathogenic mechanisms of Guillain Barré syndrome.
(John Griffin, Tony Ho, Guy McKhann)
Clinical features
of HIV-associated sensory neuropathy. (David
Cornblath)
Mechanisms of
cell death in stroke. (Valina Dawson)
Neuronal degeneration
in Parkinson's disease. (Ted Dawson)
Use of electrocorticography
in epilepsy patients. (Ronald Lesser,
Nathan Crone)
Mechanisms of
eye movement control and their application in neuro-otology.
(David Zee)
Rett's syndrome.
(Saku Naidu)
Skin biopsy: a
new window for the study of sensory neuropathies. (John
Griffin, Justin McArthur)
Clinical features
of ataxia telangiectasia. (Thomas Crawford)
Mechanisms of
pelvic pain. (Ursula Wesselmann)
Markers and determinants
of Alzheimer's disease. (Claudia
Kawas)
Neurotoxicity
of methamphetamine and Ecstasy. (George
Ricaurte)
The role of monocyte
macrophage activation in HIV-associated dementia.
(Suzanne Gartner, Katherine Conant)
Functional MRI
in localization of cognitive function.
(John Hart)
Patterns of cognitive
decline after coronary artery bypass grafting. (Guy
McKhann, Ola Selnes)
Virus isolation
and diagnostic methods in progressive multifocal leukoencephalopathy.
(Les Weiner, Opendra Narayan, John Penney, Richard Johnson)
First work on
visna in sheep in the US. (Opendra Narayan)
Immunopathogenesis
of post-infectious encephalomyelitis.
(Richard Johnson, Diane Griffin)
Mechanisms of
immune suppression by measles virus.
(Diane Griffin, Richard Johnson)
Role of immune
responses in acute encephalitis. (Diane
Griffin)
Role of viruses
in causing congenital malformations in animals.
(Richard Johnson)
Finding MBP in
CSF in human demyelinating diseases.
(Steve Cohen, Guy McKhann)
Glutamate cytotoxicity.
(Mike Johnston)
Lead developmental
disorders. (Gary Goldstein)
Blood-brain barrier
models in brain tumors. (John Laterra)
Neurobehavioral
abnormalities. (Martha Denckla)
Basal ganglion
circuits. (Mahlon Delong, Garrett Alexander)
First described
the role of movement in development of joints; pathogenesis of arthrogryposis
multiplex congenita and clubfoot. (which is the most common congenital
malformation) (Daniel Drachman)
Mechanism of action
of botulinum toxin and use for focal dystonia.
(Daniel Drachman)
Prednisone treatment
of Duchenne muscular dystrophy. (Daniel
Drachman)
Initial description
of immunotherapeutic strategies for autoimmune neuromuscular diseases.
(Daniel Drachman)
Neurotoxicity
of ibogaine. (Elizabeth O'Hearn, Mark
Molliver)
Hemispherectomy
for refractory epilepsy. (John Freeman,
Patty Vining, Sumio Uematsu)
Restless legs
syndrome: pathophysiology and treatment.
(Christopher Earley, Richard Allen)
Neonatal seizures
and hypoxic encephalopathy. (Rebecca
Ichord)
Treatment of normal
pressure hydrocephalus. (Michael Williams)
Neurogenetics
of mitochondrial diseases. (Orest Hurko,
Don Johns)
Monocyte trafficking
in encephalitis. (David Irani)
Memory disturbance.
(Barry Gordon)
.... and
many others unnamed!
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