02-Dec-2002

Anne M. Comi, M.D. Dr. Anne Comi has been a member of the Department of Neurology since July 1996. She is an Assistant Professor of Neurology with specialization in Pediatric Neurology. Particular areas of focus are the neurobiology of Sturge-Weber Syndrome (SWS). She is the Director of the Johns Hopkins - Kennedy Krieger Sturge-Weber Syndrome Center and has served on the research board of the National Sturge-Weber Foundation. Dr. Comi's clinical practice expertise includes the evaluation and management of Sturge-Weber Syndrome, epilepsy, migraine and pervasive developmental disorders. Current areas of research are the clinical, molecular, and neuropathologic study of patients with Sturge-Weber Syndrome. Dr. Comi sees patients by referral in the Neurological Outpatient Center on Mondays from 1:00 PM to 5:00 PM. Appointments may be scheduled by referral and by calling her office at 410-614-5807. CURRENT ADDRESS The Johns Hopkins Hospital Department of Neurology Jefferson Building, Room 123 600 N. Wolfe Street Baltimore, MD 21287 Phone: 410-614-5807 Fax: 410-614-2297 E-Mail: acomi@jhmi.edu EDUCATION & TRAINING 1989, BA, College of the Holy Cross, Worcester, MA 1993, MD, State University of New York at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY 1993-94, Intern in Pediatrics, Children's Hospital of Buffalo, Buffalo, NY 1994-96, Resident in Pediatrics, Children's Hospital of Buffalo, Buffalo, NY 1996-1999, Resident in Pediatric Neurology, Johns Hopkins Hospital, Baltimore, MD CURRENT APPOINTMENTS Assistant Professor of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD Active Staff, The Johns Hopkins Hospital, Baltimore, MD HONORS & AWARDS 1982, Phi Beta Kappa 1988, O'Brian Research Fund Recipient 1989, Holy Cross Dana Scholar 1989, Phi Beta Kappa 1989, Alpha Sigma Nu Honor Society 1993, Janet M. Glascow Achievement Citation, American Medical Women's Association 1999, NIH Neurological Scientist Academic Development Award CERTIFICATIONS 1998, American Board of Pediatrics 2000, American Board of Neurology and Psychiatry, with special certification in Pediatric Neurology REPRESENTATIVE PUBLICATIONS Comi, A.M., Kossoff E.H., and Fischer R. The spectrum of Sturge-Weber Syndrome variants: Encephalofacial angiomatosis sparing the occipital lobe and without facial nevus. Journal of Child Neurology, in press.. Comi, A.M., Hunt, P., Vawter, M.P., Pardo, C.A., Becker, K., and Pevsner, J. Increased fibronectin expression in Sturge-Weber Syndrome Fibroblasts and Brain Tissue. Pediatric Research, in press. Calantuoni C, Comi A, Purcell AE, Pevsner J. The use of microarrays to study childhood developmental brain disorders. Current Genomics 2002, 3,21-31. Comi A. Sturge-Weber Syndrome. Entry in The NORD Guide to Rare Diseases; Lippencott, 2002 Comi A. The Learning Disabled Child (Hyperactivity/ Dyslexia) in Current Therapy in Neurologic Disease, Sixth Edition ed. by Richard T. Johnson, John Griffin and Justin McArthur. Mosby, Inc. 2002. Adler, Mark D., Comi, A.M. and Allen R. Walker. A report of an acute hemorrhagic complication of diagnostic lumbar puncture. (2001) Pediatric Emergency Care, 17:184-8. Abstracts Anne M. Comi , Eric Kossoff, Edward Gratz and Richard Fischer. Leptomeningeal Angioma Sparing the Occipital Lobe and without Facial Nevus: On the Spectrum of Sturge-Weber Syndrome Variants? Accepted for poster at Child Neurology Society meeting, October 2002. Comi, A.M. Decreased Expression of Type II Thyroxine Deiodinase and Neurogranin in Sturge-Weber Syndrome Surgical Brain Tissue. Poster at Developmental Cerebral Blood Flow and Metabolism Meeting, June 2002. Comi, A.M. Decreased Expression of Neuro-endocrine Genes in Sturge-Weber Syndrome Surgical Brain Tissue. Oral presentation at 54th Annual Meeting of the American Academy of Neurology April 2002. Comi, A.M., Vawter, M., Pardo, C.A., Becker, K., and Pevsner, J. Differences in Gene Expression of Extracellular Matrix Molecules Found By Microarray Analysis of Sturge-Weber Syndrome Brain Tissue and Fibroblasts. Platform presentation at 30th Annual Meeting Child Neurology Society, October, 2001. Comi, A.M., Vawter, M., Calountoni, C., Bouton, C., Pardo, C.A., Becker, K. and Pevsner, J. Gene Expression Profiling in Surgical Brain Tissue and Fibroblasts from the Port-Wine Skin of Subjects with Sturge-Weber Syndrome. Platform presentation at May 2001 Annual Meeting of the American Academy of Neurology. Comi, A.M., Hunt, P. and Pevsner, J. Growth Patterns and Microarray Gene Expression in Fibroblasts Grown from Port-Wine Stain and Unaffected Skin of a Subject with Sturge-Weber Syndrome. Platform presentation. 29th Annual Meeting Child Neurology Society, October, 2000.