Restless Legs Syndrome

RLS Studies

"Intravenous Iron Metabolismin Restless Legs Syndrome"

NA-00003078

Summary In this study, we hope to learn whether or not we can bring about similar responses to high doses of intravenous iron using a new special formulation of iron (VIT 45) and whether changes in RLS symptoms relate to changes in brain iron stores. No form of intravenous iron has been approved by the FDA for treating RLS. Therefore, the iron infusion being used in this study for the treatment of RLS is considered experimental.
Length All subjects will be admitted to the General Clinical Research Center (GCRC) at Johns Hopkins for a 4 day visit, and a 3 day visit 2 weeks later. Subjects will have periodic blood draws and questionnaires for at least 12 weeks.
Compensation
There is no compensation for participation, but your travel will be either prepaid or reimbursed to you.
Inclusion Criteria
  • Must meet all the criteria for RLS.
  • Have greater than 15 periodic leg movements per hour when tested prior to treatment.
  • Your usual sleep times are between 9 PM and 9 AM.
  • Your RLS symptoms would occur daily if you were not on medication.

If you would be interested in participating in a clinical studies being conducted at the Johns Hopkins Center for RLS, please call the RLS Center Study Recruiter at 410-550-2252.


Johns Hopkins Neurology & Neurosurgery Hopkins Medicine